Up-regulation and Sustained Activation of Stat1 Are Essential for Interferon-γ (IFN-γ)-induced Dual Oxidase 2 (Duox2) and Dual Oxidase A2 (DuoxA2) Expression in Human Pancreatic Cancer Cell Lines

Dual oxidase 2 is a member of the NADPH oxidase (Nox) gene family that plays a critical role in the biosynthesis of thyroid hormone as well as in the inflammatory response of the upper airway mucosa and in wound healing, presumably through its ability to generate reactive oxygen species, including H...

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Autores principales: Wu, Yongzhong, Antony, Smitha, Juhasz, Agnes, Lu, Jiamo, Ge, Yun, Jiang, Guojian, Roy, Krishnendu, Doroshow, James H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Bioenergetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069428/
https://ncbi.nlm.nih.gov/pubmed/21321110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191031
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