Philadelphia-positive acute lymphoblastic leukemia patients already harbor BCR-ABL kinase domain mutations at low levels at the time of diagnosis

BACKGROUND: In patients with Philadelphia-positive acute lymphoblastic leukemia, resistance to treatment with tyrosine kinase inhibitors is frequent and most often associated with the development of point mutations in the BCR-ABL kinase domain. We aimed to assess: (i) in how many patients BCR-ABL ki...

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Detalhes bibliográficos
Main Authors: Soverini, Simona, Vitale, Antonella, Poerio, Angela, Gnani, Alessandra, Colarossi, Sabrina, Iacobucci, Ilaria, Cimino, Giuseppe, Elia, Loredana, Lonetti, Annalisa, Vignetti, Marco, Paolini, Stefania, Meloni, Giovanna, di Maio, Valeria, Papayannidis, Cristina, Amabile, Marilina, Guarini, Anna, Baccarani, Michele, Martinelli, Giovanni, Foà, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069232/
https://ncbi.nlm.nih.gov/pubmed/21193419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.034173
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