The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party

BACKGROUND: Recently, in genome-wide analyses of DNA copy number abnormalities using single nucleotide polymorphism microarrays, genetic alterations targeting PAX5 were identified in over 30% of pediatric patients with acute lymphoblastic leukemia. So far the occurrence of PAX5 alterations and their...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Iacobucci, Ilaria, Lonetti, Annalisa, Paoloni, Francesca, Papayannidis, Cristina, Ferrari, Anna, Storlazzi, Clelia Tiziana, Vignetti, Marco, Cilloni, Daniela, Messa, Francesca, Guadagnuolo, Viviana, Paolini, Stefania, Elia, Loredana, Messina, Monica, Vitale, Antonella, Meloni, Giovanna, Soverini, Simona, Pane, Fabrizio, Baccarani, Michele, Foà, Robin, Martinelli, Giovanni
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Ferrata Storti Foundation 2010
Θέματα:
Original Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948093/
https://ncbi.nlm.nih.gov/pubmed/20534699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.020792
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