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Evolutionary approach to predicting the binding site residues of a protein from its primary sequence
Protein binding site residues, especially catalytic residues, play a central role in protein function. Because more than 99% of the ∼12 million protein sequences in the nonredundant protein database have no structural information, it is desirable to develop methods to predict the binding site residu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069214/ https://ncbi.nlm.nih.gov/pubmed/21402946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102210108 |
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