Novel reagents for chemical cleavage at abasic sites and UV photoproducts in DNA.
Hot piperidine is often used to cleave abasic and UV-irradiated DNA at the sites of damage. It can inflict non-specific damage on DNA, probably because it is a strong base and creates significant concentrations of hydroxyl ions which can attack purines and pyrimidines. We show that several other ami...
Gardado en:
| Publicado en: | Nucleic Acids Res |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
1995
|
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7784169/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.10.1664 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|