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Determinism and stochasticity during maturation of the zebrafish antibody repertoire
It is thought that the adaptive immune system of immature organisms follows a more deterministic program of antibody creation than is found in adults. We used high-throughput sequencing to characterize the diversifying antibody repertoire in zebrafish over five developmental time points. We found th...
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Hoofdauteurs: | , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
National Academy of Sciences
2011
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069157/ https://ncbi.nlm.nih.gov/pubmed/21393572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014277108 |
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