DNMT3L Is a Regulator of X Chromosome Compaction and Post-Meiotic Gene Transcription

Previous studies on the epigenetic regulator DNA methyltransferase 3-Like (DNMT3L), have demonstrated it is an essential regulator of paternal imprinting and early male meiosis. Dnmt3L is also a paternal effect gene, i.e., wild type offspring of heterozygous mutant sires display abnormal phenotypes...

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Main Authors: Zamudio, Natasha M., Scott, Hamish S., Wolski, Katja, Lo, Chi-Yi, Law, Charity, Leong, Dillon, Kinkel, Sarah A., Chong, Suyinn, Jolley, Damien, Smyth, Gordon K., de Kretser, David, Whitelaw, Emma, O'Bryan, Moira K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069080/
https://ncbi.nlm.nih.gov/pubmed/21483837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018276
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