Towards an In Vitro Model of Plasmodium Hypnozoites Suitable for Drug Discovery

BACKGROUND: Amongst the Plasmodium species in humans, only P. vivax and P. ovale produce latent hepatic stages called hypnozoites, which are responsible for malaria episodes long after a mosquito bite. Relapses contribute to increased morbidity, and complicate malaria elimination programs. A single...

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Hauptverfasser: Dembele, Laurent, Gego, Audrey, Zeeman, Anne-Marie, Franetich, Jean-François, Silvie, Olivier, Rametti, Armelle, Le Grand, Roger, Dereuddre-Bosquet, Nathalie, Sauerwein, Robert, van Gemert, Geert-Jan, Vaillant, Jean-Christophe, Thomas, Alan W., Snounou, Georges, Kocken, Clemens H. M., Mazier, Dominique
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069045/
https://ncbi.nlm.nih.gov/pubmed/21483865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018162
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