Chloroquine Potentiates Primaquine Activity against Active and Latent Hepatic Plasmodia Ex Vivo: Potentials and Pitfalls

For a long while, 8-aminoquinoline compounds have been the only therapeutic agents against latent hepatic malaria parasites. These have poor activity against the blood-stage plasmodia causing acute malaria and must be used in conjunction with partner blood schizontocidal agents. We examined the impa...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Autores principales: Dembélé, Laurent, Franetich, Jean-François, Soulard, Valérie, Amanzougaghene, Nadia, Tajeri, Shahin, Bousema, Teun, van Gemert, Geert-Jan, Le Grand, Roger, Dereuddre-Bosquet, Nathalie, Baird, J. Kevin, Mazier, Dominique, Snounou, Georges
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927800/
https://ncbi.nlm.nih.gov/pubmed/33077656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01416-20
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