Transgenic Fluorescent Plasmodium cynomolgi Liver Stages Enable Live Imaging and Purification of Malaria Hypnozoite-Forms

A major challenge for strategies to combat the human malaria parasite Plasmodium vivax is the presence of hypnozoites in the liver. These dormant forms can cause renewed clinical disease after reactivation through unknown mechanisms. The closely related non-human primate malaria P. cynomolgi is a fr...

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Hlavní autoři: Voorberg-van der Wel, Annemarie, Zeeman, Anne-Marie, van Amsterdam, Sandra M., van den Berg, Alexander, Klooster, Els J., Iwanaga, Shiroh, Janse, Chris J., van Gemert, Geert-Jan, Sauerwein, Robert, Beenhakker, Niels, Koopman, Gerrit, Thomas, Alan W., Kocken, Clemens H. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554669/
https://ncbi.nlm.nih.gov/pubmed/23359816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054888
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