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Transgenic Fluorescent Plasmodium cynomolgi Liver Stages Enable Live Imaging and Purification of Malaria Hypnozoite-Forms

A major challenge for strategies to combat the human malaria parasite Plasmodium vivax is the presence of hypnozoites in the liver. These dormant forms can cause renewed clinical disease after reactivation through unknown mechanisms. The closely related non-human primate malaria P. cynomolgi is a fr...

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Detalhes bibliográficos
Main Authors: Voorberg-van der Wel, Annemarie, Zeeman, Anne-Marie, van Amsterdam, Sandra M., van den Berg, Alexander, Klooster, Els J., Iwanaga, Shiroh, Janse, Chris J., van Gemert, Geert-Jan, Sauerwein, Robert, Beenhakker, Niels, Koopman, Gerrit, Thomas, Alan W., Kocken, Clemens H. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554669/
https://ncbi.nlm.nih.gov/pubmed/23359816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054888
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