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Design of Allele Specific PCR for Rapid Detection of CYP3A5 (A6986G) and Mdr-1 (C3435T) Polymorphisms

Single nucleotide polymorphisms in CYP3A5 (A6986G) and MDR-1 (C3435T) genes have been shown to be associated with the pharmacokinetics of tacrolimus in case of renal transplant recipients. Knowing these genotypes of the recipients before undergoing transplantation, is therefore essential for physici...

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Autors principals: Ashavaid, Tester F., Raje, Himanshu S., Shah, Bharat V., Shah, Swarup A.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068768/
https://ncbi.nlm.nih.gov/pubmed/22211008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12291-010-0085-z
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