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Design of Allele Specific PCR for Rapid Detection of CYP3A5 (A6986G) and Mdr-1 (C3435T) Polymorphisms

Single nucleotide polymorphisms in CYP3A5 (A6986G) and MDR-1 (C3435T) genes have been shown to be associated with the pharmacokinetics of tacrolimus in case of renal transplant recipients. Knowing these genotypes of the recipients before undergoing transplantation, is therefore essential for physici...

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Bibliografiske detaljer
Main Authors: Ashavaid, Tester F., Raje, Himanshu S., Shah, Bharat V., Shah, Swarup A.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068768/
https://ncbi.nlm.nih.gov/pubmed/22211008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12291-010-0085-z
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