Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans.

We have developed a long-extension-PCR strategy which amplifies approximately half of the mitochondrial genome (6.3 kb) of Caenorhabditis elegans using an individual worm as target. We analyzed three strains over their life span to assess the number of detectable deletions in the mitochondrial genom...

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Detaylı Bibliyografya
Asıl Yazarlar: Melov, S, Lithgow, G J, Fischer, D R, Tedesco, P M, Johnson, T E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC306871/
https://ncbi.nlm.nih.gov/pubmed/7753635
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