Geroscience approaches to increase healthspan and slow aging

Por Melov, Simon
Publicado no F1000Res (2016)

SOD2 in Mitochondrial Dysfunction and Neurodegeneration

Por Flynn, James M., Melov, Simon
Publicado em 2013

Translational Geroscience: Emphasizing function to achieve optimal longevity

Por Seals, Douglas R., Melov, Simon
Publicado no Aging (Albany NY) (2014)

Gene expression changes associated with aging in C. elegans.

Por Golden, Tamara R, Melov, Simon
Publicado no WormBook (2007)

Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress.

Por Lithgow, G J, White, T M, Melov, S, Johnson, T E
Publicado em 1995

Multi-organ characterization of mitochondrial genomic rearrangements in ad libitum and caloric restricted mice show striking somatic mitochondrial DNA rearrangements with age.

Por Melov, S, Hinerfeld, D, Esposito, L, Wallace, D C
Publicado em 1997

Cellular senescence: a link between cancer and age-related degenerative disease?

Por Campisi, Judith, Andersen, Julie, Kapahi, Pankaj, Melov, Simon
Publicado em 2011

Single Cell Transcriptional Profiling of Adult Mouse Cardiomyocytes

Por Flynn, James M., Santana, Luis F., Melov, Simon
Publicado em 2011

Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle.

Por Melov, S, Shoffner, J M, Kaufman, A, Wallace, D C
Publicado em 1995

Detection of deletions in the mitochondrial genome of Caenorhabditis elegans.

Por Melov, S, Hertz, G Z, Stormo, G D, Johnson, T E
Publicado em 1994

Pleiotropic age-dependent effects of mitochondrial dysfunction on epidermal stem cells

Por Velarde, Michael C., Demaria, Marco, Melov, Simon, Campisi, Judith
Publicado no Proc Natl Acad Sci U S A (2015)

Human Embryonic Stem Cells Express Elevated Levels of Multiple Pro-Apoptotic BCL-2 Family Members

Por Madden, David T., Davila-Kruger, Diana, Melov, Simon, Bredesen, Dale E.
Publicado em 2011

Correction: Human Embryonic Stem Cells Express Elevated Levels of Multiple Pro-Apoptotic BCL-2 Family Members

Por Madden, David T., Davila-Kruger, Diana, Melov, Simon, Bredesen, Dale E.
Publicado em 2012

cep-1/p53-dependent dysplastic pathology of the aging C. elegans gonad

Por McGee, Mathew D., Day, Nicholas, Graham, Jill, Melov, Simon
Publicado em 2012

Resistance exercise reverses aging in human skeletal muscle.

Por Simon Melov, Mark A Tarnopolsky, Kenneth Beckman, Krysta Felkey, Alan Hubbard
Publicado em 2007-05-01

Pol II–Expressed shRNA Knocks Down Sod2 Gene Expression and Causes Phenotypes of the Gene Knockout in Mice

Por Xia, Xu-Gang, Zhou, Hongxia, Samper, Enrique, Melov, Simon, Xu, Zuoshang
Publicado em 2006

Resistance Exercise Reverses Aging in Human Skeletal Muscle

Por Melov, Simon, Tarnopolsky, Mark A., Beckman, Kenneth, Felkey, Krysta, Hubbard, Alan
Publicado em 2007

Single Cell Gene Expression Profiling of Cortical Osteoblast Lineage Cells

Por Flynn, James M., Spusta, Steven C., Rosen, Clifford J., Melov, Simon
Publicado em 2012

Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans.

Por Melov, S, Lithgow, G J, Fischer, D R, Tedesco, P M, Johnson, T E
Publicado em 1995

Age-related behaviors have distinct transcriptional profiles in C.elegans

Por Golden, Tamara R., Hubbard, Alan, Dando, Caroline, Herren, Michael A., Melov, Simon
Publicado em 2008