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Mitochondrial and plasma membrane lactate transporter and lactate dehydrogenase isoform expression in breast cancer cell lines

We hypothesized that dysregulation of lactate/pyruvate (monocarboxylate) transporters (MCT) and lactate dehydrogenase (LDH) isoforms contribute to the Warburg effect in cancer. Therefore, we assayed for the expression levels and the localizations of MCT (1, 2, and 4), and LDH (A and B) isoforms in b...

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Detalhes bibliográficos
Main Authors: Hussien, Rajaa, Brooks, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068517/
https://ncbi.nlm.nih.gov/pubmed/21177384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00177.2010
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