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Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle

To evaluate the potential role of mitochondrial lactate dehydrogenase (LDH) in tissue lactate clearance and oxidation in vivo, isolated rat liver, cardiac, and skeletal muscle mitochondria were incubated with lactate, pyruvate, glutamate, and succinate. As well, α-cyano-4-hydroxycinnamate (CINN), a...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Brooks, George A., Dubouchaud, Hervé, Brown, Marcia, Sicurello, James P., Butz, C. Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15362/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927705/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.3.1129
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