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Role of mitochondrial lactate dehydrogenase and lactate oxidation in the intracellular lactate shuttle

To evaluate the potential role of mitochondrial lactate dehydrogenase (LDH) in tissue lactate clearance and oxidation in vivo, isolated rat liver, cardiac, and skeletal muscle mitochondria were incubated with lactate, pyruvate, glutamate, and succinate. As well, α-cyano-4-hydroxycinnamate (CINN), a...

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Autors principals: Brooks, George A., Dubouchaud, Hervé, Brown, Marcia, Sicurello, James P., Butz, C. Eric
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15362/
https://ncbi.nlm.nih.gov/pubmed/9927705
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