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Evidence for the Mitochondrial Lactate Oxidation Complex in Rat Neurons: Demonstration of an Essential Component of Brain Lactate Shuttles

To evaluate the presence of components of a putative Intracellular Lactate Shuttle (ILS) in neurons, we attempted to determine if monocarboxylate (e.g. lactate) transporter isoforms (MCT1 and -2) and lactate dehydrogenase (LDH) are coexpressed in neuronal mitochondria of rat brains. Immunohistochemi...

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Detalhes bibliográficos
Main Authors: Hashimoto, Takeshi, Hussien, Rajaa, Cho, Hyung-Sook, Kaufer, Daniela, Brooks, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488371/
https://ncbi.nlm.nih.gov/pubmed/18698340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002915
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