CD45 Deficiency Drives Amyloid-β Peptide Oligomers and Neuronal Loss in Alzheimer's Disease Mice

Converging lines of evidence indicate dysregulation of the key immunoregulatory molecule CD45 (also known as leukocyte common antigen) in Alzheimer's disease (AD). We report that transgenic mice overproducing amyloid-β peptide (Aβ) but deficient in CD45 (PSAPP/CD45(−/−) mice) faithfully recapit...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zhu, Yuyan, Hou, Huayan, Rezai-Zadeh, Kavon, Giunta, Brian, Ruscin, Amanda, Gemma, Carmelina, Jin, JingJi, Dragicevic, Natasa, Bradshaw, Patrick, Rasool, Suhail, Glabe, Charles G., Ehrhart, Jared, Bickford, Paula, Mori, Takashi, Obregon, Demian, Town, Terrence, Tan, Jun
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2011
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068193/
https://ncbi.nlm.nih.gov/pubmed/21273420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3268-10.2011
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים