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EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP

Estrogen depletion following menopause has been correlated with an increased risk of developing Alzheimer’s disease (AD). We previously explored the beneficial effect of (-)-epigallocatechin-3-gallate (EGCG) on AD mice and found increased non-amyloidogenic processing of amyloid precursor protein (AP...

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Sonraí Bibleagrafaíochta
Main Authors: Fernandez, Jamie Winderbaum, Rezai-Zadeh, Kavon, Obregon, Demian, Tan, Jun
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981607/
https://ncbi.nlm.nih.gov/pubmed/20849853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.09.022
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