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The Alternative Splice Variant of Protein Tyrosine Kinase 6 Negatively Regulates Growth and Enhances PTK6-Mediated Inhibition of β-Catenin

Protein tyrosine kinase 6 (PTK6), also called breast tumor kinase (BRK), is expressed in epithelial cells of various tissues including the prostate. Previously it was shown that PTK6 is localized to epithelial cell nuclei in normal prostate, but becomes cytoplasmic in human prostate tumors. PTK6 is...

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Bibliografiske detaljer
Main Authors: Brauer, Patrick M., Zheng, Yu, Evans, Mark D., Dominguez-Brauer, Carmen, Peehl, Donna M., Tyner, Angela L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068133/
https://ncbi.nlm.nih.gov/pubmed/21479203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014789
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