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Rhesus Rotavirus Entry into a Polarized Epithelium Is Endocytosis Dependent and Involves Sequential VP4 Conformational Changes

Rotavirus (RV) cell entry is an incompletely understood process, involving VP4 and VP7, the viral proteins composing the outermost layer of the nonenveloped RV triple-layered icosahedral particle (TLP), encasing VP6. VP4 can exist in three conformational states: soluble, cleaved spike, and folded ba...

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Detalhes bibliográficos
Main Authors: Wolf, Marie, Vo, Phuoc T., Greenberg, Harry B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067957/
https://ncbi.nlm.nih.gov/pubmed/21191022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02082-10
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