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N-Terminal Phosphorylation of HP1α Promotes Its Chromatin Binding

The phosphorylation of heterochromatin protein 1 (HP1) has been previously described in studies of mammals, but the biological implications of this modification remain largely elusive. Here, we show that the N-terminal phosphorylation of HP1α plays a central role in its targeting to chromatin. Recom...

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Détails bibliographiques
Auteurs principaux: Hiragami-Hamada, Kyoko, Shinmyozu, Kaori, Hamada, Daizo, Tatsu, Yoshiro, Uegaki, Koichi, Fujiwara, Shinsuke, Nakayama, Jun-ichi
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067897/
https://ncbi.nlm.nih.gov/pubmed/21245376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01012-10
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