N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity

Heterochromatin protein 1 (HP1) is an evolutionarily conserved chromosomal protein that binds to lysine 9-methylated histone H3 (H3K9me), a hallmark of heterochromatin. Although HP1 phosphorylation has been described in several organisms, the biological implications of this modification remain large...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Nishibuchi, Gohei, Machida, Shinichi, Osakabe, Akihisa, Murakoshi, Hiromu, Hiragami-Hamada, Kyoko, Nakagawa, Reiko, Fischle, Wolfgang, Nishimura, Yoshifumi, Kurumizaka, Hitoshi, Tagami, Hideaki, Nakayama, Jun-ichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227797/
https://ncbi.nlm.nih.gov/pubmed/25332400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku995
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