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Rotavirus VP2 Core Shell Regions Critical for Viral Polymerase Activation

The innermost VP2 core shell of the triple-layered, icosahedral rotavirus particle surrounds the viral genome and RNA processing enzymes, including the RNA-dependent RNA polymerase (VP1). In addition to anchoring VP1 within the core, VP2 is also an essential cofactor that triggers the polymerase to...

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Autores principales: McDonald, Sarah M., Patton, John T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067889/
https://ncbi.nlm.nih.gov/pubmed/21248043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02360-10
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