Expression of the Human Endogenous Retrovirus (HERV) Group HML-2/HERV-K Does Not Depend on Canonical Promoter Elements but Is Regulated by Transcription Factors Sp1 and Sp3

After fixation in the human genome, human endogenous retroviruses (HERVs) are bona fide cellular genes despite their exogenous origin. To be able to spread within the germ line and the early embryo, the ancient retroviral promoters must have adapted to the requirements for expression in these cell t...

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Detalhes bibliográficos
Main Authors: Fuchs, Nina V., Kraft, Martin, Tondera, Christiane, Hanschmann, Kay-Martin, Löwer, Johannes, Löwer, Roswitha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067833/
https://ncbi.nlm.nih.gov/pubmed/21248046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02539-10
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