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Antiviral Activity of Human Immunodeficiency Virus Type 1 Gag-Specific Cytotoxic T Lymphocyte Targeting Is Not Necessarily Intrinsically Superior to Envelope Targeting

Across several cohorts, human immunodeficiency virus type 1 (HIV-1) Gag- and Env-specific CD8(+) T lymphocyte (CTL) responses have demonstrated inverse and positive correlations, respectively, to viremia. The mechanism has been proposed to be superior antiviral activity of Gag-specific CTLs in gener...

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Bibliografske podrobnosti
Main Authors: Chen, Diana Y., Balamurugan, Arumugam, Ng, Hwee L., Yang, Otto O.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067792/
https://ncbi.nlm.nih.gov/pubmed/21159882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01726-10
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