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Retrovirus-Induced Spongiform Neurodegeneration Is Mediated by Unique Central Nervous System Viral Targeting and Expression of Env Alone

Certain murine leukemia viruses (MLVs) can induce progressive noninflammatory spongiform neurodegeneration similar to that caused by prions. The primary MLV determinants responsible have been mapped to within the env gene; however, it has remained unclear how env mediates disease, whether non-Env vi...

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Detalles Bibliográficos
Main Authors: Li, Ying, Cardona, Sandra M., Traister, Russell S., Lynch, William P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067788/
https://ncbi.nlm.nih.gov/pubmed/21191010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02210-10
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