Retrovirus-Induced Spongiform Neurodegeneration Is Mediated by Unique Central Nervous System Viral Targeting and Expression of Env Alone

Certain murine leukemia viruses (MLVs) can induce progressive noninflammatory spongiform neurodegeneration similar to that caused by prions. The primary MLV determinants responsible have been mapped to within the env gene; however, it has remained unclear how env mediates disease, whether non-Env vi...

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Hlavní autoři: Li, Ying, Cardona, Sandra M., Traister, Russell S., Lynch, William P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067788/
https://ncbi.nlm.nih.gov/pubmed/21191010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02210-10
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