Characterization and Manipulation of the Pathway-Specific Late Regulator AlpW Reveals Streptomyces ambofaciens as a New Producer of Kinamycins

The genome sequence of Streptomyces ambofaciens, a species known to produce the congocidine and spiramycin antibiotics, has revealed the presence of numerous gene clusters predicted to be involved in the biosynthesis of secondary metabolites. Among them, the type II polyketide synthase-encoding alp...

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Bibliographic Details
Main Authors: Bunet, Robert, Song, Lijiang, Mendes, Marta Vaz, Corre, Christophe, Hotel, Laurence, Rouhier, Nicolas, Framboisier, Xavier, Leblond, Pierre, Challis, Gregory L., Aigle, Bertrand
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Physiology and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067597/
https://ncbi.nlm.nih.gov/pubmed/21193612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01269-10
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