Mucosal Vaccination with a Multivalent, Live-Attenuated Vaccine Induces Multifactorial Immunity against Pseudomonas aeruginosa Acute Lung Infection

Many animal studies investigating adaptive immune effectors important for protection against Pseudomonas aeruginosa have implicated opsonic antibody to the antigenically variable lipopolysaccharide (LPS) O antigens as a primary effector. However, active and passive vaccination of humans against thes...

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Autores principales: Kamei, Akinobu, Coutinho-Sledge, Yamara S., Goldberg, Joanna B., Priebe, Gregory P., Pier, Gerald B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067523/
https://ncbi.nlm.nih.gov/pubmed/21149583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01139-10
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