An In Vivo High-Throughput Screening Approach Targeting the Type IV Secretion System Component VirB8 Identified Inhibitors of Brucella abortus 2308 Proliferation

As bacterial pathogens develop resistance against most currently used antibiotics, novel alternatives for treatment of microbial infectious diseases are urgently needed. Targeting bacterial virulence functions in order to disarm pathogens represents a promising alternative to classical antibiotic th...

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Detalhes bibliográficos
Main Authors: Paschos, Athanasios, den Hartigh, Andreas, Smith, Mark A., Atluri, Vidya L., Sivanesan, Durga, Tsolis, Renée M., Baron, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067494/
https://ncbi.nlm.nih.gov/pubmed/21173315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00993-10
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