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Mice Lacking Components of Adaptive Immunity Show Increased Brucella abortus virB Mutant Colonization

The Brucella abortus type IV secretion system (T4SS), encoded by the virB genes, is essential for survival in mononuclear phagocytes in vitro. In the mouse model, a B. abortus virB mutant was initially able to colonize the spleen at the level of the wild type for approximately 3 to 5 days, which coi...

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Bibliographic Details
Main Authors: Rolán, Hortensia García, Tsolis, Renée M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932909/
https://ncbi.nlm.nih.gov/pubmed/17420243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01896-06
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