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Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activity

VirB8-like proteins are essential components of type IV secretion systems, bacterial virulence factors that mediate the translocation of effector molecules from many bacterial pathogens into eukaryotic cells. Based on cell biological, genetic, and x-ray crystallographic data, VirB8 was proposed to u...

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Autors principals: Paschos, Athanasios, Patey, Gilles, Sivanesan, Durga, Gao, Chan, Bayliss, Richard, Waksman, Gabriel, O'Callaghan, David, Baron, Christian
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464329/
https://ncbi.nlm.nih.gov/pubmed/16648257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600862103
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