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Swapping of Periplasmic Domains between Brucella suis VirB8 and a pSB102 VirB8 Homologue Allows Heterologous Complementation

A Brucella suis mutant with a nonpolar deletion in the virB8 gene was attenuated in a macrophage infection model. Complementation with the B. suis VirB8 protein expressed from the virB promoter restored virulence. Expression of TraJ, a VirB8 homologue from plasmid pSB102, did not restore virulence;...

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Autors principals: Patey, Gilles, Qi, Zhong, Bourg, Gisele, Baron, Christian, O'Callaghan, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539617/
https://ncbi.nlm.nih.gov/pubmed/16861687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00584-06
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