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Detection of point mutations with a modified ligase chain reaction (Gap-LCR).

DNA amplification systems are powerful technologies with the potential to impact a wide range of diagnostic applications. In this study we explored the feasibility and limitations of a modified ligase chain reaction (Gap-LCR) in detection and discrimination of DNAs that differ by a single base. LCR...

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Autori principali: Abravaya, K, Carrino, J J, Muldoon, S, Lee, H H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC306737/
https://ncbi.nlm.nih.gov/pubmed/7534908
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