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Single Quantum Dot Analysis Enables Multiplexed Point Mutation Detection by Gap Ligase Chain Reaction

Gene point mutations present important biomarkers for genetic diseases. However, existing point mutation detection methods suffer from low sensitivity, specificity, and tedious assay processes. In this report, we propose an assay technology which combines the outstanding specificity of gap ligase ch...

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Bibliografiske detaljer
Main Authors: Song, Yunke, Zhang, Yi, Wang, Tza-Huei
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963288/
https://ncbi.nlm.nih.gov/pubmed/23239594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/smll.201202242
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