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Sensitive Detection of HBsAg Mutants by a Gap Ligase Chain Reaction Assay
Hepatitis B virus (HBV) surface gene variants have been associated with diagnostic escape and immune escape following vaccination. The most common mutation observed in these variants is a glycine-to-arginine substitution at amino acid 145 (G145R). In order to sensitively detect the presence of this...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2002
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC120587/ https://ncbi.nlm.nih.gov/pubmed/12089278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.40.7.2566-2571.2002 |
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