Intra- and Extracellular Activities of Dicloxacillin and Linezolid against a Clinical Staphylococcus aureus Strain with a Small-Colony-Variant Phenotype in an In Vitro Model of THP-1 Macrophages and an In Vivo Mouse Peritonitis Model

The small-colony-variant (SCV) phenotype of Staphylococcus aureus has been associated with difficult-to-treat infections, reduced antimicrobial susceptibility, and intracellular persistence. This study represents a detailed intra- and extracellular investigation of a clinical wild-type (WT) S. aureu...

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Detalhes bibliográficos
Main Authors: Sandberg, Anne, Lemaire, Sandrine, Van Bambeke, Françoise, Tulkens, Paul M., Hughes, Diarmaid, von Eiff, Christof, Frimodt-Møller, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067142/
https://ncbi.nlm.nih.gov/pubmed/21282430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00205-10
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