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A new mutation in 16S rRNA of Escherichia coli conferring spectinomycin resistance.

We report a novel mutation, C1066U in 16S rRNA which was selected for resistance to spectinomycin, an antibiotic which inhibits ribosomal translocation. The minimal inhibitory concentration (MIC) of spectinomycin determined for this mutant (15 micrograms/ml) is greater than with the wild-type plasmi...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Johanson, U, Hughes, D
Format: Artigo
Language:Inglês
Published: Oxford University Press 1995
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306698/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7885842/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.3.464
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