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A new mutation in 16S rRNA of Escherichia coli conferring spectinomycin resistance.

We report a novel mutation, C1066U in 16S rRNA which was selected for resistance to spectinomycin, an antibiotic which inhibits ribosomal translocation. The minimal inhibitory concentration (MIC) of spectinomycin determined for this mutant (15 micrograms/ml) is greater than with the wild-type plasmi...

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Pubblicato in:Nucleic Acids Res
Autori principali: Johanson, U, Hughes, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1995
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306698/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7885842/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.3.464
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