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A new mutation in 16S rRNA of Escherichia coli conferring spectinomycin resistance.

We report a novel mutation, C1066U in 16S rRNA which was selected for resistance to spectinomycin, an antibiotic which inhibits ribosomal translocation. The minimal inhibitory concentration (MIC) of spectinomycin determined for this mutant (15 micrograms/ml) is greater than with the wild-type plasmi...

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Détails bibliographiques
Auteurs principaux: Johanson, U, Hughes, D
Format: Artigo
Langue:Inglês
Publié: 1995
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC306698/
https://ncbi.nlm.nih.gov/pubmed/7885842
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