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p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain.
We have previously reported that wild-type p53 can bind single-stranded (ss) DNA ends and catalyze renaturation of ss complementary DNA molecules. Here we demonstrate that p53 can also bind to internal segments of ss DNA molecules via a binding site (internal DNA site) distinct from the binding site...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
1995
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| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306684/ https://ncbi.nlm.nih.gov/pubmed/7885831 |
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