p53 binds single-stranded DNA ends through the C-terminal domain and internal DNA segments via the middle domain.

We have previously reported that wild-type p53 can bind single-stranded (ss) DNA ends and catalyze renaturation of ss complementary DNA molecules. Here we demonstrate that p53 can also bind to internal segments of ss DNA molecules via a binding site (internal DNA site) distinct from the binding site...

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Dettagli Bibliografici

Pubblicato in:	Nucleic Acids Res
Autori principali:	Bakalkin, G, Selivanova, G, Yakovleva, T, Kiseleva, E, Kashuba, E, Magnusson, K P, Szekely, L, Klein, G, Terenius, L, Wiman, K G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1995
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7885831/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.3.362
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