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Divalent metal ion binding to a conserved wobble pair defining the upstream site of cleavage of group I self-splicing introns.
The upstream site of cleavage of all group I self-splicing introns is identified by an absolutely conserved U.G base pair. Although a wobble C.A pair can substitute the U.G pair, all other combinations of nucleotides at this position abolish splicing, suggesting that it is an unusual RNA structure,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1995
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306681/ https://ncbi.nlm.nih.gov/pubmed/7885828 |
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