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The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation

The expression of DCC (deleted in colorectal cancer) is often markedly reduced in colorectal and other cancers. However, the rarity of point mutations identified in DCC coding sequences and the lack of a tumor predisposition phenotype in DCC hemizygous mice have raised questions about its role as a...

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Détails bibliographiques
Auteurs principaux: Forcet, Christelle, Ye, Xin, Granger, Laure, Corset, Véronique, Shin, Hwain, Bredesen, Dale E., Mehlen, Patrick
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC30668/
https://ncbi.nlm.nih.gov/pubmed/11248093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051378298
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