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The dependence receptor DCC requires lipid raft localization for cell death signaling

DCC (deleted in colorectal cancer) is a putative tumor suppressor gene whose expression is lost in numerous cancers. DCC also encodes the main receptor for the neuronal navigation cue netrin-1. It has been shown that DCC belongs to the so-called family of dependence receptors. Such receptors induce...

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Detalhes bibliográficos
Main Authors: Furne, Céline, Corset, Véronique, Hérincs, Zoltán, Cahuzac, Nathalie, Hueber, Anne-Odile, Mehlen, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449658/
https://ncbi.nlm.nih.gov/pubmed/16537496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507864103
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