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The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease

The RET (rearranged during transfection) proto-oncogene encodes a tyrosine kinase receptor involved in both multiple endocrine neoplasia type 2 (MEN 2), an inherited cancer syndrome, and Hirschsprung disease (HSCR), a developmental defect of enteric neurons. We report here that the expression of RET...

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Detalhes bibliográficos
Main Authors: Bordeaux, Marie-Claire, Forcet, Christelle, Granger, Laure, Corset, Véronique, Bidaud, Christelle, Billaud, Marc, Bredesen, Dale E., Edery, Patrick, Mehlen, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC306592/
https://ncbi.nlm.nih.gov/pubmed/10921886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.4056
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