7-Ketocholesterol–Induced Inflammation: Involvement of Multiple Kinase Signaling Pathways via NFκB but Independently of Reactive Oxygen Species Formation

PURPOSE. 7-Ketocholesterol (7KCh) accumulates in oxidized lipoprotein deposits and is known to be involved in macrophage foam cell formation and atherosclerosis. 7-KCh is present in the primate retina and is associated with oxidized lipoprotein deposits located in the choriocapillaris, Bruch's...

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Main Authors: Larrayoz, Ignacio M., Huang, Jiahn-Dar, Lee, Jung Wha, Pascual, Iranzu, Rodríguez, Ignacio R.
Format: Artigo
Language:Inglês
Published: Association for Research in Vision and Ophthalmology, Inc. 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066624/
https://ncbi.nlm.nih.gov/pubmed/20554621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4854
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