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Sterculic acid antagonizes 7-ketocholesterol-mediated inflammation and inhibits choroidal neovascularization

Sterculic acid is a cyclopropene fatty acid with numerous biological activities. In this study we demonstrate that sterculic acid is a potent inhibitor of endoplasmic reticulum (ER) stress and related inflammation caused by 7-ketocholesterol (7KCh). 7KCh is a highly toxic oxysterol suspected in the...

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Detalhes bibliográficos
Main Authors: Huang, Jiahn-Dar, Amaral, Juan, Lee, Jung Wha, Larrayoz, Ignacio M., Rodriguez, Ignacio R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307944/
https://ncbi.nlm.nih.gov/pubmed/22342272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2012.01.013
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