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Involvement of reactive oxygen species in cyclic stretch-induced NF-κB activation in human fibroblast cells

1. Uniaxial cyclic stretch leads to an upregulation of cyclooxygenase (COX)-2 through increases in the intracellular Ca(2+) concentration via the stretch-activated (SA) channel and following nuclear factor kappa B (NF-κB) activation in human fibroblasts. However, the signaling mechanism as to how th...

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Detalhes bibliográficos
Main Authors: Amma, Hideki, Naruse, Keiji, Ishiguro, Naoki, Sokabe, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576145/
https://ncbi.nlm.nih.gov/pubmed/15778740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706182
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